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Embedded sensors for Micro Transdermal Interface Platforms (MicroTIPs)

Authors: 

Conor O'Mahony, Andrea Bocchino, Eleonora Sulas, Antonio Ciarlone, Guiseppe Giannoni, Suzanne O'Callaghan, Anan Kenthao, A James, P Clover, Danilo Demarchi, Paul Galvin, Konstantin Grygoryev

Publication Type: 
Refereed Conference Meeting Proceeding
Abstract: 
Wearable `smart patches' of the future will incorporate microneedle technologies that painlessly interact with the body, using closed-loop theranostic systems to continuously monitor the physiological status of the body and deliver appropriate therapeutic agents when needed. Among other components, these Micro Transdermal Interface Platforms (MicroTIPs) will require embedded sensors to verify that the patch is operating as intended. In this paper, we integrate hollow microneedles with miniaturized pressure and impedance sensors to create an inline sensor subsystem suitable for integration with such a smart patch. Preliminary experimental work using an ex-vivo skin model shows that the sensors are capable of detecting microneedle skin insertion and removal, and of monitoring fluidic pressure and detecting leaks during the delivery phase.
Conference Name: 
2016 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP)
Proceedings: 
IEEE Proceedings of 2016 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP)
Digital Object Identifer (DOI): 
10.1109/DTIP.2016.7514859
Publication Date: 
02/06/2016
Conference Location: 
Hungary
Research Group: 
Institution: 
Tyndall National Institute
Open access repository: 
No